Pathophysiological features of the visual cycle, cascade and metabolic pathways in retinitis pigmentosa

This literature review offers a detailed description of the genes and proteins involved in pathophysiological processes isolated retinitis pigmentosa (RP). To date, 84 7 candidate have been described for non-syndromic RP. Each these encodes protein that plays role vital retina / or retinal pigment epithelium, including cascade phototransduction (transmission visual signal), cycle, ciliary transport, environment photoreceptor cilia interphotoreceptor matrix. The identification study pathways affected RP is important understanding main pathogenic ways developing approaches to target treatment.